abstract：BACKGROUND:Recent studies have analyzed the potential of advanced endoscopic imaging techniques for differentiating hyperplastic and adenomatous colorectal lesions. Latest endoscopic resection techniques now also allow for treatment of more advanced staged lesions including treatment of early cancerous lesions. AIMS:T...

journal_title：Journal of clinical gastroenterology

authors： Albrecht H,Nägel A,Tasdelen H,Rath T,Grauer M,Vieth M,Neurath MF,Neumann H

更新日期：2016-11-01 00:00:00

abstract：:Celiac disease (CD) is the most common autoimmune enteropathy, triggered by a deregulated immune response to gliadin. It has been hypothesized that human intestinal microbiota may interfere with the pathogenesis of the disease and in the clinical course of CD. In the present review, we analyzed the microbiota alterati...

journal_title：Journal of clinical gastroenterology

authors： Losurdo G,Principi M,Iannone A,Ierardi E,Di Leo A

更新日期：2016-11-01 00:00:00

abstract：:The consistent technical and conceptual progress in the study of the microbiota has led novel impulse to the research for therapeutical application of probiotic bacteria in human pathologies, such as inflammatory bowel disease (IBD). Considering the heterogenous results of probiotics in clinical studies, the model of ...

journal_title：Journal of clinical gastroenterology

authors： Pagnini C,Martorelli M,Lanini C,Delle Fave G

更新日期：2016-11-01 00:00:00

abstract：:The statements produced by the Chairmen of the 2nd International Symposium on Diverticular Disease, held in Rome on April 8th to 9th, 2016, are reported. Topics such as epidemiology, risk factors, diagnosis, medical and surgical treatment of diverticular disease in patients with uncomplicated and complicated diverticu...

journal_title：Journal of clinical gastroenterology

authors： Tursi A,Picchio M,Elisei W,Di Mario F,Scarpignato C,Brandimarte G

更新日期：2016-10-01 00:00:00

abstract：:Associations between diverticular disease of the colon and the colorectal cancer has been studied for >60 years. Observational, cross-sectional, and case-control studies as well as large population-based studies gave conflicting results and association was not fully proven. Obtaining the proof was difficult because bo...

journal_title：Journal of clinical gastroenterology

authors： Regula J

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Symptomatic uncomplicated diverticular disease (SUDD) is a common gastrointestinal disease, because it affects about one fourth of the patient harboring colonic diverticula. GOAL:To assess the effectiveness of mesalazine in improving symptoms (namely abdominal pain) and in preventing diverticulitis occurren...

journal_title：Journal of clinical gastroenterology

authors： Picchio M,Elisei W,Brandimarte G,Di Mario F,Malfertheiner P,Scarpignato C,Tursi A

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Management of diverticular disease (DD) remains a point of debate. GOALS:To investigate the current opinion of participants of the 2nd International Symposium on Diverticular Disease, on real-life management of patients with DD of the colon. STUDY:Twelve questions were aimed at the diagnosis, treatment, an...

journal_title：Journal of clinical gastroenterology

authors： Tursi A,Picchio M,Elisei W,Di Mario F,Scarpignato C,Brandimarte G

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Recently, an increasing interest to nonmotor symptoms of Parkinson disease (PD) has shown. Gastrointestinal dysfunction is a prominent nonmotor manifestation of PD and precedes motor symptoms for several years. Neuropathologic studies show early accumulation of α-synuclein (α-SYN) in Lewy neurites and Lewy...

journal_title：Journal of clinical gastroenterology

authors： Mrabet S,Ben Ali N,Achouri A,Dabbeche R,Najjar T,Haouet S,Belal S

更新日期：2016-10-01 00:00:00

abstract：GOALS:Our primary goal was to evaluate whether anti-tumor necrosis factor (TNF)-α trough levels above author-determined thresholds are associated with increased rates of mucosal healing among patients with Crohn's disease and ulcerative colitis. BACKGROUND:The introduction of anti-TNF agents has considerably advanced ...

journal_title：Journal of clinical gastroenterology

authors： Barnes EL,Allegretti JR

更新日期：2016-10-01 00:00:00

abstract：GOAL:The goal of this study was to evaluate the safety of propofol when used by gastroenterologists in patients who have an inadequate response to standard sedation (narcotics and benzodiazepines). BACKGROUND:Many patients fail to achieve adequate sedation from narcotics and benzodiazepines during colonoscopy. The adm...

journal_title：Journal of clinical gastroenterology

authors： Okeke FC,Shaw S,Hunt KK,Korsten MA,Rosman AS

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND AIMS:This study evaluated the clinical significance of subclinical ascites in patients with hepatitis B virus-related cirrhosis treated with lamivudine (LMV) or entecavir (ETV). METHODS:This multicenter retrospective study involved 8 hospitals. Patients were classified by degree of ascites: (1) no ascit...

journal_title：Journal of clinical gastroenterology

authors： Yim SY,Lee JH,Ahn H,Kim SU,Kim SG,Kim YS,Kim JH,Choe WH,Kim TY,Jung YK,Suh SJ,Suk KT,An H,Yim HJ,Seo YS,Um SH

更新日期：2016-09-01 00:00:00

abstract：GOALS:The aim of this study was to analyze the incidence and associated charges of fecal impaction for trends in hospital and patient demographics in emergency departments (ED) across the United States. BACKGROUND:In 2010, an ICD-9-CM code (560.32) for fecal impaction was introduced, allowing for assessment of fecal i...

journal_title：Journal of clinical gastroenterology

authors： Corban C,Sommers T,Sengupta N,Jones M,Cheng V,Friedlander E,Bollom A,Lembo A

更新日期：2016-08-01 00:00:00

abstract：GOALS:To determine postpartum hepatitis B virus (HBV) laboratory testing rates and identify factors associated with a lack of follow-up testing in Massachusetts. BACKGROUND:Screening for HBV infection in pregnant women is standard of care. Guidelines recommend that patients with chronic HBV have ongoing care and labor...

journal_title：Journal of clinical gastroenterology

authors： Chang MS,Barton K,Crockett M,Tuomala RE,Rutherford AE,Mutinga ML,Andersson KL,Brown RS Jr,Oken E,Ukomadu C

更新日期：2016-07-01 00:00:00

abstract：:Intestinal failure (IF) is a state in which the nutritional demands are not met by the gastrointestinal absorptive surface. A majority of IF cases are associated with short-bowel syndrome, which is a result of malabsorption after significant intestinal resection for numerous reasons, some of which include Crohn's dise...

journal_title：Journal of clinical gastroenterology

authors： Bharadwaj S,Tandon P,Meka K,Rivas JM,Jevenn A,Kuo NT,Steiger E

更新日期：2016-05-01 00:00:00

abstract：GOALS:To describe a multicenter experience using an endoscopic suturing device for management of gastrointestinal (GI) defects and stent anchorage. BACKGROUND:Endoscopic closure of GI defects including perforations, fistulas, and anastomotic leaks as well as stent anchorage has improved with technological advances. An...

journal_title：Journal of clinical gastroenterology

authors： Sharaiha RZ,Kumta NA,DeFilippis EM,Dimaio CJ,Gonzalez S,Gonda T,Rogart J,Siddiqui A,Berg PS,Samuels P,Miller L,Khashab MA,Saxena P,Gaidhane MR,Tyberg A,Teixeira J,Widmer J,Kedia P,Loren D,Kahaleh M,Sethi A

更新日期：2016-05-01 00:00:00

abstract：GOAL:Our aim was to investigate fecal microbiota transplantation (FMT) efficacy in patients with severe and/or complicated Clostridium difficile infection (CDI). BACKGROUND:FMT is successful for recurrent CDI, although its benefit in severe or complicated CDI has not specifically been evaluated. STUDY METHODS:A multi...

journal_title：Journal of clinical gastroenterology

authors： Aroniadis OC,Brandt LJ,Greenberg A,Borody T,Kelly CR,Mellow M,Surawicz C,Cagle L,Neshatian L,Stollman N,Giovanelli A,Ray A,Smith R

更新日期：2016-05-01 00:00:00

abstract：GOALS:The aim of this study was to compare celecoxib with loxoprofen for protection of small intestine. BACKGROUND:RCT studies report that COX-2 selective inhibitor celecoxib induces fewer small intestinal injuries than nonselective nonsteroidal anti-inflammatory drugs (NSAIDs). Loxoprofen is a prodrug nonselective NS...

journal_title：Journal of clinical gastroenterology

authors： Fujimori S,Hanada R,Hayashida M,Sakurai T,Ikushima I,Sakamoto C

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Moderate sedation has been standard for noninvasive gastrointestinal procedures for decades yet there are limited data on reversal agent use and outcomes associated with need for reversal of sedation. AIM:To determine prevalence and clinical significance of reversal agent use during endoscopies and colonosc...

journal_title：Journal of clinical gastroenterology

authors： Hung A,Marshall J,Barnett S,Falchuk ZM,Sawhney M,Leffler DA

更新日期：2016-03-01 00:00:00

abstract：GOALS:To investigate the association between treatment nonadherence and patients' knowledge of the prescribed medication among individuals with inflammatory bowel disease (IBD), and evaluate the impact of nonadherence on relapse. BACKGROUND:The patient's knowledge of the prescribed medication has been identified as an...

journal_title：Journal of clinical gastroenterology

authors： Tae CH,Jung SA,Moon HS,Seo JA,Song HK,Moon CM,Kim SE,Shim KN,Jung HK

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Celiac disease (CeD) is a systemic disease with manifestations not limited to small intestine. The data on association between CeD and infertility is contradictory. There are no recommendations for the screening of female patients with infertility for CeD. AIM:We conducted a meta-analysis to find out whethe...

journal_title：Journal of clinical gastroenterology

authors： Singh P,Arora S,Lal S,Strand TA,Makharia GK

更新日期：2016-01-01 00:00:00

abstract：:Many lines of research have established a relationship between the gut microbiome and patients with liver disease. For example, patients with cirrhosis have increased bacteremia, increased blood levels of lipopolysaccharide, and increased intestinal permeability. Patients with cirrhosis have bacterial overgrowth in th...

journal_title：Journal of clinical gastroenterology

authors： Brenner DA,Paik YH,Schnabl B

更新日期：2015-11-01 00:00:00

abstract：:Microbial signals stimulate development and maintenance of the neonatal immune system. The process begins in utero, with limited exposure to microbes in the intrauterine environment, as well as maternal immune signals priming the developing immune system. After birth and initial colonization, the immune system must be...

journal_title：Journal of clinical gastroenterology

authors： Houghteling PD,Walker WA

更新日期：2015-11-01 00:00:00

abstract：:Gastrointestinal leaks and fistulae are common postoperative complications, whereas intestinal perforation more commonly complicates advanced endoscopic procedures. Although these complications have classically been managed surgically, there exists an ever-expanding role for endoscopic therapy and the involvement of a...

journal_title：Journal of clinical gastroenterology

authors： Rustagi T,McCarty TR,Aslanian HR

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Poor preparation for elective colonoscopy is exceedingly common in persons with spinal cord injury (SCI). This unsatisfactory outcome is likely due to long-standing difficulty with evacuation and decreased colonic motility, which may result in inadequate responses to conventional bowel preparation regimens. ...

journal_title：Journal of clinical gastroenterology

authors： Korsten MA,Spungen AM,Radulovic M,Rosman AS,Hunt K,Galea MD,Kornfeld SD,Lyons BL,Yen C,Bauman WA

更新日期：2015-10-01 00:00:00

abstract：GOALS:We sought to determine if providers who have higher standards for optimal bowel preparation might be more fastidious in their examination of the colon and, therefore, have higher adenoma detection rates (ADRs). BACKGROUND:ADRs are a reliable and objective marker of colonoscopy performance. Suboptimal bowel prepa...

journal_title：Journal of clinical gastroenterology

authors： Mahadev S,Green PH,Lebwohl B

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Mortality from ST elevation myocardial infarction (STEMI) is decreasing nationwide, but no report to date examined STEMI mortality among patients with cirrhosis. GOALS:Determine mortality rates and investigate possible disparities in cardiovascular interventions for patients with and without cirrhosis admit...

journal_title：Journal of clinical gastroenterology

authors： Abougergi MS,Karagozian R,Grace ND,Saltzman JR,Qamar AA

更新日期：2015-10-01 00:00:00

abstract：GOAL:We hypothesized that sleeping left-side down with the head/torso elevated reduces recumbent gastroesophageal reflux (GER). BACKGROUND:Previous studies show that sleeping with head of bed elevated or on wedge reduces GER and lying left-side down reduces GER versus right-side down and supine. No prior studies have ...

journal_title：Journal of clinical gastroenterology

authors： Person E,Rife C,Freeman J,Clark A,Castell DO

更新日期：2015-09-01 00:00:00

abstract：:Dieulafoy's lesion (DL) is a persistently wide caliber artery that is observed more frequently at the fifth decade of life in the male population with multiple comorbidities. There are a variety of endoscopic therapies that have been used to treat DL; however, there are no clear guidelines on the best treatment modali...

journal_title：Journal of clinical gastroenterology

authors： Nguyen DC,Jackson CS

更新日期：2015-08-01 00:00:00

abstract：GOALS:Our study reexamines the prevalence of interval colorectal cancer (I-CRC) by manually reviewing CRC cases at a single institution. BACKGROUND:In 2% to 8% of patients with CRC, diagnosis occurs during the interval 6 to 36 months after a cancer-free colonoscopy. Rates are often determined by linking the date of co...

journal_title：Journal of clinical gastroenterology

authors： Gotfried J,Bernstein M,Ehrlich AC,Friedenberg FK

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Duodenal intraepithelial lymphocytosis (D-IEL) is an early marker for celiac disease (CD). However, the majority of cases are due to non-CD-related conditions. GOALS:To identify the predictors of CD when presented with D-IEL. METHODS:A total of 215 adult patients with D-IEL had undergone prospective and sy...

journal_title：Journal of clinical gastroenterology

authors： Aziz I,Key T,Goodwin JG,Sanders DS

更新日期：2015-07-01 00:00:00

abstract：:With the development of high-resolution manometry and specific metrics to characterize esophageal motility, the Chicago Classification has become the gold standard for the diagnosis of esophageal motor disorders. Major and significant disorders, that is, never observed in healthy subjects, are achalasia, esophagogastr...

journal_title：Journal of clinical gastroenterology

authors： Zerbib F,Roman S

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND AIM:Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease. The objective of this study was to describe the recent trend of health care resource utilization and short-term mortality of Medicare beneficiaries with NAFLD. METHODS:This study utilized data from a ...

journal_title：Journal of clinical gastroenterology

authors： Younossi ZM,Zheng L,Stepanova M,Henry L,Venkatesan C,Mishra A

更新日期：2015-03-01 00:00:00

abstract：:Over the last 2 decades, endoscopic ultrasound (EUS) has evolved from a noninvasive diagnostic tool to a combined diagnostic and therapeutic modality. The use of EUS complementary to endoscopic retrograde cholangiopancreatography (ERCP) has made possible biliary and pancreatic drainage in situations where conventional...

journal_title：Journal of clinical gastroenterology

authors： Gavini H,Lee JH

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Several biomarkers have been proposed for the diagnosis of autoimmune atrophic gastritis (AAG), but at the present there is no appropriate testing strategy for the disease. GOALS:The aim of this study was to develop and validate a laboratory score able to address the diagnosis of AAG in a general practice s...

journal_title：Journal of clinical gastroenterology

authors： Miceli E,Padula D,Lenti MV,Gallia A,Albertini R,Di Stefano M,Klersy C,Corazza GR

更新日期：2015-01-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor, originally described in adipose tissue, which controls the expression of a large number of regulatory genes in lipid metabolism and insulin sensitization. Well known by endocrinologists, thiazolidinedionesare classical PPARγ synthetic agonists...

journal_title：Journal of clinical gastroenterology

authors： Speca S,Dubuquoy L,Desreumaux P

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Leaky gut, or intestinal permeability, is the phenomenon of the gut wall exhibiting increased absorbency. It is pretty well recognised that an altered or damaged bowel lining or gut wall may result from unbalanced diet, parasites, infection, or medications and that this allows substances such as toxins, micr...

journal_title：Journal of clinical gastroenterology

authors： Del Piano M,Balzarini M,Carmagnola S,Pagliarulo M,Tari R,Nicola S,Deidda F,Pane M

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Urinary tract infections (UTIs) are the most common bacterial infection in women. Most UTIs are acute uncomplicated cystitis caused by Escherichia coli (86%). This study was undertaken to assess the effectiveness of an association of a cranberry dry extract, D-mannose, a gelling complex composed of the exopo...

journal_title：Journal of clinical gastroenterology

authors： Vicariotto F

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND AIMS:There is no study verifying the predictive value of model for end-stage liver disease and sodium (MELD-Na) for rebleeding and its associated mortality in cirrhotic patients after cessation of acute esophageal variceal hemorrhage (AVH) by endoscopic therapy. This study aimed to determine the predicti...

journal_title：Journal of clinical gastroenterology

authors： Wang J,Wang AJ,Li BM,Liu ZJ,Chen L,Wang H,Shi F,Zhu X

更新日期：2014-11-01 00:00:00

abstract：:Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms comprising only 1% to 2% of all pancreatic tumors. In recent years, the number of incidentally discovered PNETs has greatly increased given the widespread use of axial imaging. However, a significant proportion of PNETs may not be visualized on con...

journal_title：Journal of clinical gastroenterology

authors： Rustagi T,Farrell JJ

更新日期：2014-11-01 00:00:00

abstract：INTRODUCTION:Cirrhosis is a major milestone in patients with chronic liver disease because of its impact on patient morbidity and mortality. Chronic hepatitis B (CHB) and hepatitis C (CHC) are important causes of cirrhosis. This systematic review examines the relevant literature and evidence to assess whether cirrhosis...

journal_title：Journal of clinical gastroenterology

authors： Manne V,Akhtar E,Saab S

更新日期：2014-10-01 00:00:00